Siemens Healthineers Introduces Syngo.CT Coronary Cockpit for AI-Driven CAD Assessment
How automated plaque analysis and CT-guided planning strengthen coronary artery disease management.
www.siemens-healthineers.com

A Software Approach to Improving Coronary Artery Disease Pathways
At RSNA 2025, Siemens Healthineers unveiled Syngo.CT Coronary Cockpit, a new software application on the Syngo.via platform designed to support diagnosis and treatment planning for coronary artery disease (CAD). CAD remains the leading global cause of death and disability, creating continued demand for accurate, non-invasive tools that can help clinicians evaluate plaque burden and prepare percutaneous coronary interventions (PCI) more effectively.
The software is built for use with dual-source and photon-counting CT scanners, enabling clinicians to extract detailed plaque characteristics directly from routine cardiac CT imaging. By automating this analysis, the tool helps transform complex imaging data into actionable clinical information.
Unlocking Plaque Detail for More Precise Clinical Decisions
Syngo.CT Coronary Cockpit quantifies and characterizes coronary plaque through AI-based segmentation, labeling and visualization. It evaluates plaque composition, size and distribution, giving clinicians deeper insight into disease severity and progression. This supports decisions about whether patients may benefit most from medical management or interventional treatment.
Advances in dual-source and photon-counting CT have already positioned coronary CT angiography (CCTA) as a frontline diagnostic tool. Studies using the Naeotom Alpha photon-counting CT scanner have shown that non-invasive CCTA can substantially reduce diagnostic angiography referrals, lower costs and shorten hospital stays by improving plaque visibility and diagnostic accuracy. The new software builds on these strengths by offering direct plaque analysis and pre-procedural planning capabilities.
Supporting PCI Planning Through Non-Invasive Imaging
Integrating Syngo.CT Coronary Cockpit with Siemens Healthineers’ CT systems enhances both diagnostic confidence and interventional planning. Detailed plaque morphology and anatomy obtained before entering the cath lab can streamline procedures and improve resource utilization. The software provides information relevant to key intraprocedural decisions, including lesion preparation, stent length and landing-zone selection.
By equipping clinicians with precise, non-invasive anatomical data, the software supports personalized treatment planning and may help avoid unnecessary invasive angiography when non-invasive imaging provides sufficient clarity.
A Step Toward CT-Guided Treatment Pathways
Syngo.CT Coronary Cockpit reflects Siemens Healthineers’ broader strategy to merge CT imaging with interventional therapy planning. By making plaque analysis faster and more accessible, the software strengthens the role of CT not only as a diagnostic tool but also as a guide for therapeutic decision-making. This shift supports a future in which treatment planning—including PCI—relies increasingly on high-resolution imaging and automated analysis.
The software is currently pending 510(k) clearance and is not yet commercially available in the United States. Availability of Syngo.via and its software options varies by country due to regulatory conditions.
www.siemens-healthineers.com

