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BD, HAMILTON COLLABORATE TO STANDARDIZE SINGLE-CELL MULTIOMICS EXPERIMENTS USING ROBOTICS

The companies will automate a critical step of high-throughput single-cell multiomics experiments.

BD, HAMILTON COLLABORATE TO STANDARDIZE SINGLE-CELL MULTIOMICS EXPERIMENTS USING ROBOTICS
Automated applications together with robotics-compatible reagent kits to enable greater standardization and reduced human error when conducting large-scale single-cell multiomics experiments.

BD announced a collaboration agreement with Hamilton, a leading global manufacturer of laboratory automation technology, to develop automated applications together with robotics-compatible reagent kits to enable greater standardization and reduced human error when conducting large-scale single-cell multiomics experiments.

As a result of the collaboration, BD aims to deliver a suite of BD Rhapsody™ Single-Cell Analysis Library Preparation Reagent Kits that can be performed on the Hamilton Microlab® NGS STAR™ robotic liquid-handling platform. The combination will automate steps, including pipetting and thermal cycling, to produce DNA samples or "libraries" that are ready for genetic sequencing.

In single-cell multiomics experiments, constructing libraries of fragmented genetic information that can be read by sequencing instruments is an essential first step before next-generation sequencing (NGS) can be performed and insights from cells can be gathered. NGS library preparation is historically a time-intensive process with manual steps that can result in inconsistent results and compromised data quality.

"Multiomics-based assays are increasingly used by single cell researchers in the fields of oncology, immunology and other disciplines to help investigate the various layers of information on a single cell and access a deeper view of health and disease, which is why ensuring reproducible results is critical," said Steve Conly, worldwide president at BD Biosciences. "By integrating Hamilton's robotic technology into our end-to-end portfolio of single-cell multiomics solutions, BD continues to leverage automation so that more researchers — whether academic, biopharmaceutical, or contract research organization— are empowered to perform larger scale single-cell multiomics studies with confidence."

The BD Rhapsody™ Single-Cell Analysis Library Preparation Reagent Kits and Hamilton Microlab® NGS STAR™ applications will be developed and released in phases starting in 2024.

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