ABBOTT CARDIOMEMS SENSOR REDUCES HEART FAILURE HOSPITALIZATIONS BY 44%

New data presented from an investigator-sponsored European trial found managing indicated1 heart failure patients with Abbott's CardioMEMS™ HF System resulted in a significant improvement in patient-reported quality-of-life scores as early as three months after use with the remote monitoring sensor. The MONITOR-HF trial also resulted in a significant 44% reduction in heart failure-related hospitalizations among chronic heart failure patients who used guideline-directed medical therapy (GDMT). GDMT refers to the European and U.S. guidelines for heart failure management that uses a combination of up to four heart medications. MONITOR-HF is the third randomized, controlled clinical trial globally to show a significant health benefit and quality-of-life improvement for heart failure patients using the CardioMEMS HF System.

New Data Reveal Improved Quality of Life
The MONITOR-HF trial met its primary endpoint and found that heart failure participants who received a CardioMEMS sensor reported a clinically meaningful improvement in their quality-of-life as quantified by a 7-point mean increase on the Kansas City Cardiomyopathy Questionnaire's (KCCQ) score compared to patients in the control group, who did not receive the pressure sensor and whose scores decreased. In heart failure, the KCCQ is a clinical standard assessment that has been recommended to capture and measure patient-reported quality of care. The questionnaire asks patients how difficult it is to complete common activities such as walking a short distance, doing household chores and socializing with family and friends.

"The Dutch health care system is known for its structured approach to heart failure management at outpatient clinics with general access to guideline-directed medical therapies," said J.J. (Jasper) Brugts, M.D., Ph.D., principal investigator for the MONITOR-HF trial and associate professor at Erasmus Medical Center in Rotterdam, Netherlands. "This approach raises the bar, making the MONITOR-HF results even more meaningful given that patients who were already receiving a high standard of care reported significant improvements in their quality of life while using the CardioMEMS monitoring system."

The CardioMEMS sensor is a paperclip-sized device that, once placed in the pulmonary artery during a minimally invasive procedure, monitors for pressure changes that indicate worsening heart failure. It wirelessly transmits daily readings to a patient's clinical team – empowering the patient and their care team to manage their condition from virtually anywhere.